You can leave your Sister on Venus & they’ll only steal the credits you get from missions on that planet. So you shouldn’t be missing out on too much by ignoring the controlled nodes (you can always do the normal missions on those nodes too when clicked on, so not locked out of anything)
You may have more power to deal with them than you think though. The big thing will be going over the Lich/Sister system, mostly meaning you’ll need to get Requiem Mods for your Parazon as this is the only permanent way to kill your Sister
As others have mentioned, recruiting chat in-game or most of the Warframe Discords are usually willing to help with any of this if you need help too!
Very (VERY) basic overview of handling your sister if you wanted to take a stab (heh) at it.
Liches/Sisters need a “passcode” to kill. You need the correct 3 Keys (Requiem Mods) & in the correct order to actually take down your Sister.
Clearing Nodes, and killing the Hounds in these Nodes, gives murmurs which automatically unlock progress towards these Keys (Requiem Mods)
You get the mods themselves from Requiem Relics, which drop from Kuva Siphons / Kuva Floods under the Alerts tab on the starchart. Just like Void Relics, these relics need to be opened in Void Fissures (located under the Void Fissures tab on the starchart)
These mods are equipped to the Parazon (slot specific. ABC is different than CBA).
Clearing nodes, and killing Hounds, also enrages your Sister causing them to eventually spawn.
Damage the Sister, then stab them to test if your mod is in the right place. If it is, you proceed to try the second, then if correct again, the third.
Repeat the above until you have all the mods and have them in the correct order to kill you Sister. This will then send them to a Showdown located in Railjack. The enemy level here is also capped at 65.
My general disruption frame/ ability is Sevagoth & gloom, able to slow down demolysts to nearly stationary.
Then the Epitaph for cold procs & more slow against demolysts. If using Sevagoth, than also increased headshot damage.
Felarx for primary & vastilok with Shattering Impact for armor strip.
Most of the colors are from the default pallet with the blacks being from the Pride one
This is true peak fashion:
I love my Pennant. Easy red crits, guaranteed slash proc on heavy attack, and has the passive on increasing attack speed on heavy attack kill.
This is the build I use, but if you don’t have a riven would probably slot in Corrupt Charge or another Gladiator mod for the set bonus
Most of the scythes in the game, especially Reaper Prime, are also very good with this type of build (look for stances with guaranteed slash or weapons with mostly slash damage)
I like file.pizza for the off-moments I need to send a file immediately to someone.
Its essentially just a peer-to-peer tunnel so once you close the website it stops transferring the file