Could this k-hole be any worse??
Seriously though, did he OD on ketamine? Seems fairly uncommon, and like you’d need to take a decent amount?
With the rest of the findings, it’s totally within reasonable possibility. Tbh almost anything could have sent his body into a regal fatal behavior, looking at the combination of illnesses and meds on board.
Ketamine in therapeutic doses won’t often do it by itself. You can OD on enough of it, with death as a possibility. As you said, not common, and not at normal doses. But what would be a pleasant trip down the k hole for the average person isn’t a good idea for someone with pretty much any cardiovascular disease. Hell, some anaesthesiolgists won’t use it without a cardiac workup, though that’s also pretty rare from what I’ve been told.
He’d abused his body for decades. It sucks, I wish anybody struggling with addiction gets a chance to overcome it and live well. But as much as it sucks, it wouldn’t be surprising that his body just gave out under a therapeutic dose. At higher doses, it was inevitable
Multiple grams simultaneously for a healthy adult IIRC and more with a tolerance. I have to imagine it’s difficult to even snort that much in a single sitting, let alone before you become unconscious.
But remember what ketamine was originally developed for: general anesthesia. You don’t need to take enough for its toxicity to kill you, just enough to induce a coma such that you’re unable to know you’re drowning in a couple feet of hot water.
You don’t need to do multiple grams to khole.
It’s 100-250mg depending on body weight.
You might want to read the parent comment again. It was talking about a fatal OD, not a k-hole.
I mean he literally opens with “Could this k-hole be any worse??” But I see your point about the follow up question about OD
He was already suffering from physical and mental issues for years prior to his death. Maybe it would be very hard to kill a healthy person that way, maybe it wasn’t as hard in Perry’s case.
Looking back, he spiraled very slowly, then very quickly. It would shock me if foul play was involved.
I mean, from the description in this article it sounds like he did rails of K, went into the hot tub, and more than likely K-holed and drowned.
It’s not exactly farfetched. A k-hole is basically just falling asleep somewhat-maybe awake. Slipping under the water and not being able to react is entirely within reason.
This is the best summary I could come up with:
Half a year after the death of Matthew Perry from acute effects of anesthetic ketamine, the Los Angeles police department (LAPD) and Drug Enforcement Administration (DEA) have launched a joint criminal investigation looking into how the Friends star got the prescription medication, law enforcement sources confirmed to the Los Angeles Times on Tuesday.
Trace amounts of ketamine, which is sometimes used to treat depression, were found in his stomach, according to the Los Angeles medical examiner.
“At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression,” the autopsy report stated.
The autopsy also identified drowning, coronary artery disease and buprenorphine – a drug used to treat opioid addiction, about which Perry discussed openly in interviews and his 2022 memoir – as contributing factors in his death.
According to the medical examiner, Perry was undergoing ketamine infusion therapy for anxiety and depression in the days before his death.
Following the fatal accidental overdose of Mac Miller in 2018, police arrested and charged Ryan Michael Reavis for selling the rapper counterfeit, fentanyl-laced pills.
The original article contains 467 words, the summary contains 186 words. Saved 60%. I’m a bot and I’m open source!
