• knightly the Sneptaur@pawb.social
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      6 months ago

      Tbh, I’d be tempted to say “go for it!” if it weren’t for the medical liability. A doc would want to check your hormone levels before prescribing estradiol just to ensure that there aren’t any risk factors present.

      The odds of one dose fucking you up are very, very low but not zero.

      • good_girl@lemmy.blahaj.zone
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        6 months ago

        Not a doctor- but…

        There’s a reason E is normally prescribed with a testosterone blocker. Small doses of Estradiol will do next to nothing if there’s still a natural level of T flowing through your system.

        • knightly the Sneptaur@pawb.social
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          6 months ago

          Trans enby here.

          I’ve still got my “normal” levels of testostetone, but I’m taking finasteride to keep it from affecting my hair follicles while the estradiol does its work softening my skin and plumping up my chest.

          I probably could be a lot more feminine by this point if I had a full-spectrum anti-androgen like spironolactone or cyproterone acetate, but that’s not my transition goal. I’m actively seeking an androgynous appearance and itty bitty titties, so estradiol monotherapy with finasteride is working just fine for me.

    • Wirlocke@lemmy.blahaj.zone
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      6 months ago

      A single Estradiol prolly won’t do anything.

      But testosterone blockers like Spironolactone is also a heart medication, so be careful.