A human experiment in nerve division by W. H .R. Rivers MD FRS, Fellow of St John's College, Cambridge and Henry Head MD FRS, Physician to the London Hospital, Brain 1908: 31; 323–450
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Despite having studied in detail the symptoms and signs of recovery from peripheral nerve injury in patients at the London Hospital with Mr James Sherren, Dr He

From the history of pretty crazy self experimentation in medicine, a doctor has a cutaneous branch of his own radial nerve surgically cut. He then meticulously documents the progress of nerve regrowth, initial total numbness followed by neuropathic pain, and a partial return of sensation over time