I wrote the research team and have skimmed the article. Dose regimen was 0.05mg/kg every other day. This would be about 0.25mg in an adult female human. Or about 0.25g of moderate potency cubensis. Half that or less of strong cubensis (PE/APE/etc).
Researcher: Hey, rodent, do you still have mental illness?
Rodent: Squeak Squeeeeeek
Researcher: What an astounding success!
This seems kind of silly to me. This is a drug that affects the brain, and that is nearly harmless at the microdose level. Just test on human volunteers. That way your results have useful clinical meaning. You can’t really ask the rats how they felt after the regimen.
They are, but placebo makes it difficult to measure.
This study proves more is going on then placebo and will surely help more funding go into human studies.
It’s certainly not silly. But I keep pet rats and I do find the methods used in animal studies often cruel. This one included.
But it’s not silly.
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Was your dose frequency every other day?
I have a friend wanting to microdose and want her to be aware of your experience and possible withdrawal symptoms. The study used every other day which I would assume would minimize withdrawal considering psilocybin has a short half-life.
But I haven’t tried microing in years and when I did I only stuck with it for a week.
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Ahh… I’ve gone through SSRI withdrawal and I thought maybe something similar could be happening because of the repeated dosing.
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This only ever happened to me whenever I got REALLY high, I equate it to a drunken burp, people don’t really like them but I think they feel kind of good actually.
Yup. Was on venlafaxine and then duloxotine. Had to switch to Prozac and taper that.
It sucked.
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