I have a pretty strong usecase for distributed Small/Medium Business bare metal VM hosts. most locations do not need NAS/SAN, and DAS will more than suffice. lower cost hardware with a near-line raided backend and SSD hotcache at FS level seems to be a pretty decent sweet spot.

obviously this is not some enterprise grade setup and YMMV, but I am pretty interested in a all-in-one FS solution. I am sure others may have more innovative setups where its even more interesting.